Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-α gene and their associations with multiple sclerosis
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چکیده
منابع مشابه
Association study of four polymorphisms in the interleukin-7 receptor alpha gene with multiple sclerosis in Eastern Iran
Objective(s): Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS) with unknown etiology. Various genetics and environmental factors contribute to the pathogenesis of the disease. The interleukin-7 receptor alpha chain (IL-7Ra) was identified as the first non-major histocompatibility complex (non-MHC) MS susceptibility locus. In this study we are tr...
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objective(s): multiple sclerosis (ms) is an autoimmune demyelinating disease of the central nervous system (cns) with unknown etiology. various genetics and environmental factors contribute to the pathogenesis of the disease. the interleukin-7 receptor alpha chain (il-7ra) was identified as the first non-major histocompatibility complex (non-mhc) ms susceptibility locus. in this study we are tr...
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association of interleukin 7 receptor gene polymorphism rs6897932 with multiple sclerosis patients in khuzestan.
background: multiple sclerosis (ms) is a chronic inflammatory demyelinating and neurodegenerative disease of central nervous system with unknown causes. etiology of ms involves both genetic and environment factors. the interleukin 7 receptor (il7r) gene is a promising candidate for ms, because its involvement in the autoimmunity, regulation of the t-cell homeostasis...
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ژورنال
عنوان ژورنال: European Journal of Human Genetics
سال: 2003
ISSN: 1018-4813,1476-5438
DOI: 10.1038/sj.ejhg.5200994